Antitubercular, Cytotoxicity, and Computational Target Validation of Dihydroquinazolinone Derivatives

A series of 2,3-dihydroquinazolin-4(1H)-one derivatives (3a–3m) was screened for in vitro whole-cell antitubercular activity against the tubercular strain H37Rv and multidrug-resistant (MDR) Mycobacterium tuberculosis (MTB) strains. Compounds 3l and 3m with di-substituted aryl moiety (halogens) atta...

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Detalles Bibliográficos
Autores principales: Venugopala, Katharigatta N., Al-Shar’i, Nizar A., Dahabiyeh, Lina A., Hourani, Wafa, Deb, Pran Kishore, Pillay, Melendhran, Abu-Irmaileh, Bashaer, Bustanji, Yasser, Chandrashekharappa, Sandeep, Tratrat, Christophe, Attimarad, Mahesh, Nair, Anroop B., Sreeharsha, Nagaraja, Shinu, Pottathil, Haroun, Michelyne, Kandeel, Mahmoud, Balgoname, Abdulmalek Ahmed, Venugopala, Rashmi, Morsy, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311641/
https://www.ncbi.nlm.nih.gov/pubmed/35884084
http://dx.doi.org/10.3390/antibiotics11070831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311641/
https://www.ncbi.nlm.nih.gov/pubmed/35884084
http://dx.doi.org/10.3390/antibiotics11070831

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