Paclitaxel in vitro reversibly sensitizes the excitability of IB4(−) and IB4(+) sensory neurons from male and female rats

BACKGROUND AND PURPOSE: Paclitaxel produces a chemotherapy‐induced peripheral neuropathy that persists in 50–60% of cancer patients upon treatment. Evidence from animal models suggests an axonopathy of peripheral A‐ and C‐type fibres that affects their excitability. However, direct effects of paclit...

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Detalles Bibliográficos
Autores principales: Villalba‐Riquelme, Eva, de la Torre‐Martínez, Roberto, Fernández‐Carvajal, Asia, Ferrer‐Montiel, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311666/
https://www.ncbi.nlm.nih.gov/pubmed/35102580
http://dx.doi.org/10.1111/bph.15809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311666/
https://www.ncbi.nlm.nih.gov/pubmed/35102580
http://dx.doi.org/10.1111/bph.15809

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