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Total Synthesis and Structure Correction of the Cyclic Lipodepsipeptide Orfamide A
A total synthesis of the cyclic lipodepsipeptide natural product orfamide A was achieved. By developing a synthesis format using an aminoacid ester building block and SPPS protocol adaptation, a focused library of target compounds was obtained, in high yield and purity. Spectral and LC‐HRMS data of...
Autores principales: | Bando, Yuko, Hou, Yu, Seyfarth, Lydia, Probst, Jannik, Götze, Sebastian, Bogacz, Marta, Hellmich, Ute A., Stallforth, Pierre, Mittag, Maria, Arndt, Hans‐Dieter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311703/ https://www.ncbi.nlm.nih.gov/pubmed/35199896 http://dx.doi.org/10.1002/chem.202104417 |
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