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The Optimal Permeation of Cyclic Boronates to Cross the Outer Membrane via the Porin Pathway

We investigated the diffusion of three cyclic boronates formulated as beta-lactamase inhibitors through the porin OmpF to evaluate their potential to cross OM via the porin pathway. The three nonbeta-lactam molecules diffuse through the porin eyelet region with the same mechanism observed for beta-l...

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Detalles Bibliográficos
Autores principales: Tuveri, Gian Marco, Ceccarelli, Matteo, Pira, Alessandro, Bodrenko, Igor V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311757/
https://www.ncbi.nlm.nih.gov/pubmed/35884094
http://dx.doi.org/10.3390/antibiotics11070840