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The Optimal Permeation of Cyclic Boronates to Cross the Outer Membrane via the Porin Pathway
We investigated the diffusion of three cyclic boronates formulated as beta-lactamase inhibitors through the porin OmpF to evaluate their potential to cross OM via the porin pathway. The three nonbeta-lactam molecules diffuse through the porin eyelet region with the same mechanism observed for beta-l...
Autores principales: | Tuveri, Gian Marco, Ceccarelli, Matteo, Pira, Alessandro, Bodrenko, Igor V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311757/ https://www.ncbi.nlm.nih.gov/pubmed/35884094 http://dx.doi.org/10.3390/antibiotics11070840 |
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