A Novel Class of Potent Anti-Tyrosinase Compounds with Antioxidant Activity, 2-(Substituted phenyl)-5-(trifluoromethyl)benzo[d]thiazoles: In Vitro and In Silico Insights

Sixteen compounds bearing a benzothiazole moiety were synthesized as potential tyrosinase inhibitors and evaluated for mushroom tyrosinase inhibitory activity. The compound 4-(5-(trifluoromethyl)benzo[d]thiazol-2-yl)benzene-1,3-diol (compound 1b) exhibited the highest tyrosinase activity inhibition,...

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, YeJi, Lee, Jieun, Jung, Hee Jin, Ullah, Sultan, Ko, Jeongin, Jeong, Yeongmu, Park, Yu Jung, Kang, Min Kyung, Yun, Hwayoung, Kim, Min-Soo, Chun, Pusoon, Chung, Hae Young, Moon, Hyung Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311798/
https://www.ncbi.nlm.nih.gov/pubmed/35883866
http://dx.doi.org/10.3390/antiox11071375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311798/
https://www.ncbi.nlm.nih.gov/pubmed/35883866
http://dx.doi.org/10.3390/antiox11071375

Ejemplares similares