Pharmacokinetics and Safety of Doripenem in Healthy Chinese Subjects and Monte Carlo Dosing Simulations

The aim of this study was to investigate the pharmacokinetics (PK) of doripenem in healthy Chinese subjects and evaluate the optimal dosage regimens of doripenem. A randomized, single-dose, three-period, self-crossover controlled extended-infusion clinical trial was conducted with 12 healthy Chinese...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Liu, Xiaofen, Li, Kun, Fan, Yaxin, Yu, Jicheng, Wu, Hailan, Li, Yi, Wu, Xiaojie, Guo, Beining, Li, Xin, Hu, Jiali, Wu, Jufang, Cao, Guoying, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311841/
https://www.ncbi.nlm.nih.gov/pubmed/35884212
http://dx.doi.org/10.3390/antibiotics11070958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311841/
https://www.ncbi.nlm.nih.gov/pubmed/35884212
http://dx.doi.org/10.3390/antibiotics11070958

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