Population Pharmacokinetics of Temocillin Administered by Continuous Infusion in Patients with Septic Shock Associated with Intra-Abdominal Infection and Ascitic Fluid Effusion

Temocillin is active against Gram-negative bacteria, including many extended-spectrum β-lactamase (ESBL)-producing Enterobacterales. We studied its pharmacokinetics in plasma and ascitic fluid after intravenous administration of a loading dose of 2 g over 30 min, followed by continuous infusion of 6...

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Detalles Bibliográficos
Autores principales: Ngougni Pokem, Perrin, Wittebole, Xavier, Collienne, Christine, Rodriguez-Villalobos, Hector, Tulkens, Paul M., Elens, Laure, Van Bambeke, Françoise, Laterre, Pierre-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311849/
https://www.ncbi.nlm.nih.gov/pubmed/35884152
http://dx.doi.org/10.3390/antibiotics11070898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311849/
https://www.ncbi.nlm.nih.gov/pubmed/35884152
http://dx.doi.org/10.3390/antibiotics11070898

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