Potential Neurotoxic Effects of Glioblastoma-Derived Exosomes in Primary Cultures of Cerebellar Neurons via Oxidant Stress and Glutathione Depletion

High-grade gliomas are the most fatal brain tumors. Grade 4 gliomas are called glioblastoma multiforme (GBM), which are associated with the poorest survival and a 5-year survival rate of less than 4%. Many patients with GBM developed concomitant cognitive dysfunctions and epilepsy. Although the cogn...

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Detalles Bibliográficos
Autores principales: Genc, Sidika, Pennisi, Manuela, Yeni, Yesim, Yildirim, Serkan, Gattuso, Giuseppe, Altinoz, Meric A., Taghizadehghalehjoughi, Ali, Bolat, Ismail, Tsatsakis, Aristidis, Hacımüftüoğlu, Ahmet, Falzone, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311852/
https://www.ncbi.nlm.nih.gov/pubmed/35883716
http://dx.doi.org/10.3390/antiox11071225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311852/
https://www.ncbi.nlm.nih.gov/pubmed/35883716
http://dx.doi.org/10.3390/antiox11071225

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