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Mitochondrial Calcium-Triggered Oxidative Stress and Developmental Defects in Dopaminergic Neurons Differentiated from Deciduous Teeth-Derived Dental Pulp Stem Cells with MFF Insufficiency

Mitochondrial fission factor (MFF) is an adapter that targets dynamin-related protein 1 from the cytosol to the mitochondria for fission. Loss-of-function MFF mutations cause encephalopathy due to defective mitochondrial and peroxisomal fission 2 (EMPF2). To elucidate the molecular mechanisms that w...

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Detalles Bibliográficos
Autores principales: Sun, Xiao, Dong, Shuangshan, Kato, Hiroki, Kong, Jun, Ito, Yosuke, Hirofuji, Yuta, Sato, Hiroshi, Kato, Takahiro A., Sakai, Yasunari, Ohga, Shouichi, Fukumoto, Satoshi, Masuda, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311869/
https://www.ncbi.nlm.nih.gov/pubmed/35883852
http://dx.doi.org/10.3390/antiox11071361