Regulating Phase Transition in Neurodegenerative Diseases by Nuclear Import Receptors

SIMPLE SUMMARY: Aberrant protein phase transitions and aggregation trigger various neurodegenerative diseases, including ALS, FTD, Alzheimer’s disease, and Huntington’s disease. Dynamic exchange of proteins and RNA between the nucleus and cytoplasm is essential for cellular functioning, which is gre...

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Detalles Bibliográficos
Autores principales: Girdhar, Amandeep, Guo, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311884/
https://www.ncbi.nlm.nih.gov/pubmed/36101390
http://dx.doi.org/10.3390/biology11071009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311884/
https://www.ncbi.nlm.nih.gov/pubmed/36101390
http://dx.doi.org/10.3390/biology11071009

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