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Brimonidine Modulates the ROCK1 Signaling Effects on Adipogenic Differentiation in 2D and 3D 3T3-L1 Cells

The additive effects of an α2-adrenergic agonist, brimonidine (BRI), on the pan-ROCK inhibitor (ROCK-i), ripasudil (Rip), and the ROCK2-I, KD025, on adipogenic differentiation (DIF+) were examined using two- or three-dimension (2D or 3D) cultures of 3T3-L1 cells. The following analyses were carried...

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Detalles Bibliográficos
Autores principales: Umetsu, Araya, Ida, Yosuke, Sato, Tatsuya, Watanabe, Megumi, Tsugeno, Yuri, Furuhashi, Masato, Hikage, Fumihito, Ohguro, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311963/
https://www.ncbi.nlm.nih.gov/pubmed/35877378
http://dx.doi.org/10.3390/bioengineering9070327