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Soluble Epoxide Hydrolase Inhibitor t-AUCB Ameliorates Vascular Endothelial Dysfunction by Influencing the NF-κB/miR-155-5p/eNOS/NO/IκB Cycle in Hypertensive Rats

Epoxyeicosatrienoic acids (EETs), angiogenic mediators degraded by soluble epoxide hydrolase (sEH), have been shown to exert beneficial effects on the cardiovascular system. The current study assessed the impact of increased EETs with an sEH inhibitor, t-AUCB, on two-kidney-one-clip (2K1C)-induced r...

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Detalles Bibliográficos
Autores principales: Wang, Xiaorui, Han, Wenwen, Zhang, Yi, Zong, Yi, Tan, Na, Zhang, Yan, Li, Li, Liu, Chang, Liu, Limei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311992/
https://www.ncbi.nlm.nih.gov/pubmed/35883863
http://dx.doi.org/10.3390/antiox11071372