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Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD

Xanthine oxidase (XO) contributes to oxidative stress and vascular disease. Hyperuricemia and gout are common in patients with chronic kidney disease (CKD), a population at increased risk of vascular disease. We evaluated effects of allopurinol on serum XO activity and metabolome of CKD patients who...

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Detalles Bibliográficos
Autores principales: Sun, Mingyao, Hines, Nicole, Scerbo, Diego, Buchanan, Jane, Wu, Chaorong, Ten Eyck, Patrick, Zepeda-Orozco, Diana, Taylor, Eric B., Jalal, Diana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312025/
https://www.ncbi.nlm.nih.gov/pubmed/35883787
http://dx.doi.org/10.3390/antiox11071297