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Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD
Xanthine oxidase (XO) contributes to oxidative stress and vascular disease. Hyperuricemia and gout are common in patients with chronic kidney disease (CKD), a population at increased risk of vascular disease. We evaluated effects of allopurinol on serum XO activity and metabolome of CKD patients who...
Autores principales: | Sun, Mingyao, Hines, Nicole, Scerbo, Diego, Buchanan, Jane, Wu, Chaorong, Ten Eyck, Patrick, Zepeda-Orozco, Diana, Taylor, Eric B., Jalal, Diana I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312025/ https://www.ncbi.nlm.nih.gov/pubmed/35883787 http://dx.doi.org/10.3390/antiox11071297 |
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