Cargando…

Overexpression of Mitochondrial Ferritin Enhances Blood–Brain Barrier Integrity following Ischemic Stroke in Mice by Maintaining Iron Homeostasis in Endothelial Cells

Blood–brain barrier (BBB) breakdown, a characteristic feature of ischemic stroke, contributes to poor patient outcomes. Brain microvascular endothelial cells (BMVECs) are a key component of the BBB and dysfunction or death of these cells following cerebral ischemia reperfusion (I/R) injury can disru...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Peina, Ren, Qianqian, Shi, Mengtong, Liu, Yuanyuan, Bai, Huiyuan, Chang, Yan-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312053/
https://www.ncbi.nlm.nih.gov/pubmed/35883748
http://dx.doi.org/10.3390/antiox11071257