Cargando…
Overexpression of Mitochondrial Ferritin Enhances Blood–Brain Barrier Integrity following Ischemic Stroke in Mice by Maintaining Iron Homeostasis in Endothelial Cells
Blood–brain barrier (BBB) breakdown, a characteristic feature of ischemic stroke, contributes to poor patient outcomes. Brain microvascular endothelial cells (BMVECs) are a key component of the BBB and dysfunction or death of these cells following cerebral ischemia reperfusion (I/R) injury can disru...
Autores principales: | Wang, Peina, Ren, Qianqian, Shi, Mengtong, Liu, Yuanyuan, Bai, Huiyuan, Chang, Yan-Zhong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312053/ https://www.ncbi.nlm.nih.gov/pubmed/35883748 http://dx.doi.org/10.3390/antiox11071257 |
Ejemplares similares
-
Mitochondrial ferritin alleviates apoptosis by enhancing mitochondrial bioenergetics and stimulating glucose metabolism in cerebral ischemia reperfusion
por: Wang, Peina, et al.
Publicado: (2022) -
The Construction and Characterization of Mitochondrial Ferritin Overexpressing Mice
por: Li, Xin, et al.
Publicado: (2017) -
Mitochondrial ferritin in the regulation of brain iron homeostasis and neurodegenerative diseases
por: Gao, Guofen, et al.
Publicado: (2014) -
Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis
por: Wang, Peina, et al.
Publicado: (2021) -
Ginaton improves neurological function in ischemic stroke rats via inducing autophagy and maintaining mitochondrial homeostasis
por: Li, Xiaoqiang, et al.
Publicado: (2019)