The Flavonoid Hesperidin Methyl Chalcone Targets Cytokines and Oxidative Stress to Reduce Diclofenac-Induced Acute Renal Injury: Contribution of the Nrf2 Redox-Sensitive Pathway

Hesperidin is derived from citrus fruits among other plants. Hesperidin was methylated to increase its solubility, generating hesperidin methyl chalcone (HMC), an emerging flavonoid that possess anti-inflammatory and antioxidant properties. The nuclear factor erythroid 2-related factor 2 (Nrf2) is a...

Descripción completa

Detalles Bibliográficos
Autores principales: Bussmann, Allan J. C., Zaninelli, Tiago H., Saraiva-Santos, Telma, Fattori, Victor, Guazelli, Carla F. S., Bertozzi, Mariana M., Andrade, Ketlem C., Ferraz, Camila R., Camilios-Neto, Doumit, Casella, Antônio M. B., Casagrande, Rubia, Borghi, Sergio M., Verri, Waldiceu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312103/
https://www.ncbi.nlm.nih.gov/pubmed/35883752
http://dx.doi.org/10.3390/antiox11071261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312103/
https://www.ncbi.nlm.nih.gov/pubmed/35883752
http://dx.doi.org/10.3390/antiox11071261

Ejemplares similares