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The Flavonoid Hesperidin Methyl Chalcone Targets Cytokines and Oxidative Stress to Reduce Diclofenac-Induced Acute Renal Injury: Contribution of the Nrf2 Redox-Sensitive Pathway

Hesperidin is derived from citrus fruits among other plants. Hesperidin was methylated to increase its solubility, generating hesperidin methyl chalcone (HMC), an emerging flavonoid that possess anti-inflammatory and antioxidant properties. The nuclear factor erythroid 2-related factor 2 (Nrf2) is a...

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Detalles Bibliográficos
Autores principales:	Bussmann, Allan J. C., Zaninelli, Tiago H., Saraiva-Santos, Telma, Fattori, Victor, Guazelli, Carla F. S., Bertozzi, Mariana M., Andrade, Ketlem C., Ferraz, Camila R., Camilios-Neto, Doumit, Casella, Antônio M. B., Casagrande, Rubia, Borghi, Sergio M., Verri, Waldiceu A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312103/ https://www.ncbi.nlm.nih.gov/pubmed/35883752 http://dx.doi.org/10.3390/antiox11071261

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