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Synthesis and Evaluation of Novel DNA Minor Groove Binders as Antiamoebic Agents
The free-living amoeba Acanthamoeba castellanii is responsible for the central nervous infection granulomatous amoebic encephalitis and sight-threatening infection Acanthamoeba keratitis. Moreover, no effective treatment is currently present, and a combination drug therapy is used. In this study, tw...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312114/ https://www.ncbi.nlm.nih.gov/pubmed/35884189 http://dx.doi.org/10.3390/antibiotics11070935 |