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Intermittent Short-Term Infusion vs. Continuous Infusion of Piperacillin: Steady State Concentrations in Porcine Cervical Spine Tissue Evaluated by Microdialysis

Background: Piperacillin is a central drug in the treatment of Pseudomonas aeruginosa spondylodiscitis. Intermittent short-term infusion (STI) remains standard treatment in most centres, although the application of continuous infusion (CI) has shown promising results in other clinical settings. We a...

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Detalles Bibliográficos
Autores principales: Petersen, Elisabeth Krogsgaard, Hanberg, Pelle, Knudsen, Martin, Tøstesen, Sara Kousgaard, Jørgensen, Andrea René, Öbrink-Hansen, Kristina, Søballe, Kjeld, Stilling, Maiken, Bue, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312177/
https://www.ncbi.nlm.nih.gov/pubmed/35884164
http://dx.doi.org/10.3390/antibiotics11070910