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Atto488-Agitoxin 2—A Fluorescent Ligand with Increased Selectivity for Kv1.3 Channel Binding Site

Fluorescently labeled peptide blockers of ion channels are useful probes in studying the localization and functioning of the channels and in the performance of a search for new channel ligands with bioengineering screening systems. Here, we report on the properties of Atto488-agitoxin 2 (A-AgTx2), a...

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Detalles Bibliográficos
Autores principales: Denisova, Kristina R., Orlov, Nikita A., Yakimov, Sergey A., Kirpichnikov, Mikhail P., Feofanov, Alexey V., Nekrasova, Oksana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312206/
https://www.ncbi.nlm.nih.gov/pubmed/35877346
http://dx.doi.org/10.3390/bioengineering9070295