Inhibition of GCN2 Alleviates Cardiomyopathy in Type 2 Diabetic Mice via Attenuating Lipotoxicity and Oxidative Stress

Diabetic cardiomyopathy (DCM) is a kind of heart disease that affects diabetic patients and is one of the primary causes of death. We previously demonstrated that deletion of the general control nonderepressible 2 (GCN2) kinase ameliorates cardiac dysfunction in diabetic mice. The aim of this study...

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Detalles Bibliográficos
Autores principales: Yuan, Juntao, Li, Fang, Cui, Bingqing, Gao, Junling, Yu, Zhuoran, Lu, Zhongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312289/
https://www.ncbi.nlm.nih.gov/pubmed/35883870
http://dx.doi.org/10.3390/antiox11071379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312289/
https://www.ncbi.nlm.nih.gov/pubmed/35883870
http://dx.doi.org/10.3390/antiox11071379

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