B-Type Natriuretic Peptide (BNP) Revisited—Is BNP Still a Biomarker for Heart Failure in the Angiotensin Receptor/Neprilysin Inhibitor Era?

SIMPLE SUMMARY: Active BNP-32, less active proBNP-108, and inactive N-terminal proBNP-76 all circulate in the blood. The circulating protease neprilysin has lower substrate specificity for BNP than ANP, while proBNP and N-terminal proBNP are not degraded by neprilysin. Currently available BNP immuno...

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Detalles Bibliográficos
Autores principales: Nishikimi, Toshio, Nakagawa, Yasuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312360/
https://www.ncbi.nlm.nih.gov/pubmed/36101415
http://dx.doi.org/10.3390/biology11071034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312360/
https://www.ncbi.nlm.nih.gov/pubmed/36101415
http://dx.doi.org/10.3390/biology11071034

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