Loss of RNase J leads to multi-drug tolerance and accumulation of highly structured mRNA fragments in Mycobacterium tuberculosis

Despite the existence of well-characterized, canonical mutations that confer high-level drug resistance to Mycobacterium tuberculosis (Mtb), there is evidence that drug resistance mechanisms are more complex than simple acquisition of such mutations. Recent studies have shown that Mtb can acquire no...

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Detalles Bibliográficos
Autores principales: Martini, Maria Carla, Hicks, Nathan D., Xiao, Junpei, Alonso, Maria Natalia, Barbier, Thibault, Sixsmith, Jaimie, Fortune, Sarah M., Shell, Scarlet S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312406/
https://www.ncbi.nlm.nih.gov/pubmed/35830479
http://dx.doi.org/10.1371/journal.ppat.1010705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312406/
https://www.ncbi.nlm.nih.gov/pubmed/35830479
http://dx.doi.org/10.1371/journal.ppat.1010705

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