In-silico discovery of dual active molecule to restore synaptic wiring against autism spectrum disorder via HDAC2 and H3R inhibition

Metal-dependent histone deacetylases (HDACs) are essential epigenetic regulators; their molecular and pharmacological roles in medically critical diseases such as neuropsychiatric disorders, neurodegeneration, and cancer are being studied globally. HDAC2’s differential expression in the central nerv...

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Detalles Bibliográficos
Autores principales: Raja, Anupam, Shekhar, Nishant, Singh, Harvinder, Prakash, Ajay, Medhi, Bikash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312418/
https://www.ncbi.nlm.nih.gov/pubmed/35877665
http://dx.doi.org/10.1371/journal.pone.0268139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312418/
https://www.ncbi.nlm.nih.gov/pubmed/35877665
http://dx.doi.org/10.1371/journal.pone.0268139

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