MicroRNA-138-5p Targets Pro-Apoptotic Factors and Favors Neural Cell Survival: Analysis in the Injured Spinal Cord

The central nervous system microRNA miR-138-5p has attracted much attention in cancer research because it inhibits pro-apoptotic genes including CASP3. We hypothesize that miR-138-5p downregulation after SCI leads to overexpression of pro-apoptotic genes, sensitizing neural cells to noxious stimuli....

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Detalles Bibliográficos
Autores principales: Maza, Rodrigo M., Barreda-Manso, María Asunción, Reigada, David, Silván, Ágata, Muñoz-Galdeano, Teresa, Soto, Altea, del Águila, Ángela, Nieto-Díaz, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312482/
https://www.ncbi.nlm.nih.gov/pubmed/35884864
http://dx.doi.org/10.3390/biomedicines10071559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312482/
https://www.ncbi.nlm.nih.gov/pubmed/35884864
http://dx.doi.org/10.3390/biomedicines10071559

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