Telomere Dysfunction Is Associated with Altered DNA Organization in Trichoplein/Tchp/Mitostatin (TpMs) Depleted Cells

Recently, we highlighted a novel role for the protein Trichoplein/TCHP/Mitostatin (TpMs), both as mitotic checkpoint regulator and guardian of chromosomal stability. TpMs-depleted cells show numerical and structural chromosome alterations that lead to genomic instability. This condition is a major d...

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Detalles Bibliográficos
Autores principales: Lauriola, Angela, Davalli, Pierpaola, Marverti, Gaetano, Caporali, Andrea, Mai, Sabine, D’Arca, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312488/
https://www.ncbi.nlm.nih.gov/pubmed/35884905
http://dx.doi.org/10.3390/biomedicines10071602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312488/
https://www.ncbi.nlm.nih.gov/pubmed/35884905
http://dx.doi.org/10.3390/biomedicines10071602

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