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Tertiary and Quaternary Structure Organization in GMP Synthetases: Implications for Catalysis

Glutamine amidotransferases, enzymes that transfer nitrogen from Gln to various cellular metabolites, are modular, with the amidotransferase (GATase) domain hydrolyzing Gln, generating ammonia and the acceptor domain catalyzing the addition of nitrogen onto its cognate substrate. GMP synthetase (GMP...

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Detalles Bibliográficos
Autores principales: Ballut, Lionel, Violot, Sébastien, Galisson, Frédéric, Gonçalves, Isabelle R., Martin, Juliette, Shivakumaraswamy, Santosh, Carrique, Loïc, Balaram, Hemalatha, Aghajari, Nushin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312489/
https://www.ncbi.nlm.nih.gov/pubmed/35883427
http://dx.doi.org/10.3390/biom12070871