2,3,5,6-Tetramethylpyrazine Targets Epithelial-Mesenchymal Transition by Abrogating Manganese Superoxide Dismutase Expression and TGFβ-Driven Signaling Cascades in Colon Cancer Cells

Epithelial-mesenchymal transition (EMT) is a crucial process in which the polarized epithelial cells acquire the properties of mesenchymal cells and gain invasive properties. We have previously demonstrated that manganese superoxide dismutase (MnSOD) can regulate the EMT phenotype by modulating the...

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Detalles Bibliográficos
Autores principales: Jung, Young Yun, Mohan, Chakrabhavi Dhananjaya, Eng, Huiyan, Narula, Acharan S., Namjoshi, Ojas A., Blough, Bruce E., Rangappa, Kanchugarakoppal S., Sethi, Gautam, Kumar, Alan Prem, Ahn, Kwang Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312507/
https://www.ncbi.nlm.nih.gov/pubmed/35883447
http://dx.doi.org/10.3390/biom12070891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312507/
https://www.ncbi.nlm.nih.gov/pubmed/35883447
http://dx.doi.org/10.3390/biom12070891

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