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2,3,5,6-Tetramethylpyrazine Targets Epithelial-Mesenchymal Transition by Abrogating Manganese Superoxide Dismutase Expression and TGFβ-Driven Signaling Cascades in Colon Cancer Cells
Epithelial-mesenchymal transition (EMT) is a crucial process in which the polarized epithelial cells acquire the properties of mesenchymal cells and gain invasive properties. We have previously demonstrated that manganese superoxide dismutase (MnSOD) can regulate the EMT phenotype by modulating the...
Autores principales: | Jung, Young Yun, Mohan, Chakrabhavi Dhananjaya, Eng, Huiyan, Narula, Acharan S., Namjoshi, Ojas A., Blough, Bruce E., Rangappa, Kanchugarakoppal S., Sethi, Gautam, Kumar, Alan Prem, Ahn, Kwang Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312507/ https://www.ncbi.nlm.nih.gov/pubmed/35883447 http://dx.doi.org/10.3390/biom12070891 |
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