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Diminazene Aceturate Reduces Angiotensin II Constriction and Interacts with the Spike Protein of Severe Acute Respiratory Syndrome Coronavirus 2

Diminazene aceturate (DIZE) is a putative angiotensin-converting enzyme 2 (ACE2) activator and angiotensin type 1 receptor antagonist (AT(1)R). Its simple chemical structure possesses a negatively charged triazene segment that is homologous to the tetrazole of angiotensin receptor blockers (ARB), wh...

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Detalles Bibliográficos
Autores principales: Matsoukas, John M., Gadanec, Laura Kate, Zulli, Anthony, Apostolopoulos, Vasso, Kelaidonis, Konstantinos, Ligielli, Irene, Moschovou, Kalliopi, Georgiou, Nikitas, Plotas, Panagiotis, Chasapis, Christos T., Moore, Graham, Ridgway, Harry, Mavromoustakos, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312513/
https://www.ncbi.nlm.nih.gov/pubmed/35885036
http://dx.doi.org/10.3390/biomedicines10071731