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Engineering ACE2 decoy receptors to combat viral escapability

Decoy receptor proteins that trick viruses to bind to them should be resistant to viral escape because viruses that require entry receptors cannot help but bind decoy receptors. Angiotensin-converting enzyme 2 (ACE2) is the major receptor for coronavirus cell entry. Recombinant soluble ACE2 was prev...

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Detalles Bibliográficos
Autores principales: Arimori, Takao, Ikemura, Nariko, Okamoto, Toru, Takagi, Junichi, Standley, Daron M., Hoshino, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312672/
https://www.ncbi.nlm.nih.gov/pubmed/35902282
http://dx.doi.org/10.1016/j.tips.2022.06.011