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Arterial Calcifications in Patients with Liver Cirrhosis Are Linked to Hepatic Deficiency of Pyrophosphate Production Restored by Liver Transplantation

Liver fibrosis is associated with arterial calcification (AC). Since the liver is a source of inorganic pyrophosphate (PPi), an anti-calcifying compound, we investigated the relationship between plasma PPi ([PPi]pl), liver fibrosis, liver function, AC, and the hepatic expression of genes regulating...

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Detalles Bibliográficos
Autores principales: Laurain, Audrey, Rubera, Isabelle, Razzouk-Cadet, Micheline, Bonnafous, Stéphanie, Albuquerque, Miguel, Paradis, Valérie, Patouraux, Stéphanie, Duranton, Christophe, Lesaux, Olivier, Lefthériotis, Georges, Tran, Albert, Anty, Rodolphe, Gual, Philippe, Iannelli, Antonio, Favre, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312703/
https://www.ncbi.nlm.nih.gov/pubmed/35884801
http://dx.doi.org/10.3390/biomedicines10071496