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Ubiquitin-Specific Protease 6 n-Terminal-like Protein (USP6NL) and the Epidermal Growth Factor Receptor (EGFR) Signaling Axis Regulates Ubiquitin-Mediated DNA Repair and Temozolomide-Resistance in Glioblastoma

Glioblastoma multiforme (GBM) is the most malignant glioma, with a 30–60% epidermal growth factor receptor (EGFR) mutation. This mutation is associated with unrestricted cell growth and increases the possibility of cancer invasion. Patients with EGFR-mutated GBM often develop resistance to the avail...

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Detalles Bibliográficos
Autores principales: Su, I-Chang, Su, Yu-Kai, Chuang, Hao-Yu, Yadav, Vijesh Kumar, Setiawan, Syahru Agung, Fong, Iat-Hang, Yeh, Chi-Tai, Huang, Hui-Chuan, Lin, Chien-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312792/
https://www.ncbi.nlm.nih.gov/pubmed/35884836
http://dx.doi.org/10.3390/biomedicines10071531