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Effects of Lipid Lowering Therapy Optimization by PCSK9 Inhibitors on Circulating CD34+ Cells and Pulse Wave Velocity in Familial Hypercholesterolemia Subjects without Atherosclerotic Cardiovascular Disease: Real-World Data from Two Lipid Units

Background: Circulating CD34+ progenitor cells (CD34+CPCs) are characterized by pronounced tissue regeneration activity. Dyslipidemic subjects seemed to have reduced CD34+CPCs, and statin therapy appeared to restore their levels. We aimed to evaluate the effects of PCSK9 inhibitors (PCSK9-i) on CD34...

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Detalles Bibliográficos
Autores principales: Scicali, Roberto, Mandraffino, Giuseppe, Scuruchi, Michele, Lo Gullo, Alberto, Di Pino, Antonino, Ferrara, Viviana, Morace, Carmela, Aragona, Caterina Oriana, Squadrito, Giovanni, Purrello, Francesco, Piro, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312801/
https://www.ncbi.nlm.nih.gov/pubmed/35885020
http://dx.doi.org/10.3390/biomedicines10071715