Small-Molecule Inhibitors Targeting FEN1 for Cancer Therapy

DNA damage repair plays a key role in maintaining genomic stability and integrity. Flap endonuclease 1 (FEN1) is a core protein in the base excision repair (BER) pathway and participates in Okazaki fragment maturation during DNA replication. Several studies have implicated FEN1 in the regulation of...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Hu, Zhigang, Guo, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312813/
https://www.ncbi.nlm.nih.gov/pubmed/35883563
http://dx.doi.org/10.3390/biom12071007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312813/
https://www.ncbi.nlm.nih.gov/pubmed/35883563
http://dx.doi.org/10.3390/biom12071007

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