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Small-Molecule Inhibitors Targeting FEN1 for Cancer Therapy

DNA damage repair plays a key role in maintaining genomic stability and integrity. Flap endonuclease 1 (FEN1) is a core protein in the base excision repair (BER) pathway and participates in Okazaki fragment maturation during DNA replication. Several studies have implicated FEN1 in the regulation of...

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Detalles Bibliográficos
Autores principales:	Yang, Fan, Hu, Zhigang, Guo, Zhigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312813/ https://www.ncbi.nlm.nih.gov/pubmed/35883563 http://dx.doi.org/10.3390/biom12071007

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