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Zinc Modulation of Neuronal Calcium Sensor Proteins: Three Modes of Interaction with Different Structural Outcomes

Neuronal calcium sensors (NCSs) are the family of EF-hand proteins mediating Ca(2+)-dependent signaling pathways in healthy neurons and neurodegenerative diseases. It was hypothesized that the calcium sensor activity of NCSs can be complemented by sensing fluctuation of intracellular zinc, which cou...

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Detalles Bibliográficos
Autores principales: Baksheeva, Viktoriia E., Tsvetkov, Philipp O., Zalevsky, Arthur O., Vladimirov, Vasiliy I., Gorokhovets, Neonila V., Zinchenko, Dmitry V., Permyakov, Sergei E., Devred, François, Zernii, Evgeni Yu.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312857/
https://www.ncbi.nlm.nih.gov/pubmed/35883512
http://dx.doi.org/10.3390/biom12070956