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The FGFR2c/PKCε Axis Controls MCL-1-Mediated Invasion in Pancreatic Ductal Adenocarcinoma Cells: Perspectives for Innovative Target Therapies

Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy whose main characterizations are Kirsten Rat Sarcoma-activating mutations (KRAS) and a highly aggressive phenotype. Based on our recent findings demonstrating that the highly aberrant expression of the mesenchymal isoform of Fibroblast G...

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Detalles Bibliográficos
Autores principales: Ranieri, Danilo, French, Deborah, Persechino, Flavia, Guttieri, Luisa, Torrisi, Maria Rosaria, Belleudi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312859/
https://www.ncbi.nlm.nih.gov/pubmed/35884957
http://dx.doi.org/10.3390/biomedicines10071652