Therapeutic miR-506-3p Replacement in Pancreatic Carcinoma Leads to Multiple Effects including Autophagy, Apoptosis, Senescence, and Mitochondrial Alterations In Vitro and In Vivo

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer mortality. Considering its very poor prognosis, novel treatment options are urgently needed. MicroRNAs (miRNAs) are involved in the regulation of various physiological and pathological processes. In tumors, aberrant downregulation...

Descripción completa

Detalles Bibliográficos
Autores principales: Borchardt, Hannes, Kogel, Alexander, Kalwa, Hermann, Weirauch, Ulrike, Aigner, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312874/
https://www.ncbi.nlm.nih.gov/pubmed/35884996
http://dx.doi.org/10.3390/biomedicines10071692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312874/
https://www.ncbi.nlm.nih.gov/pubmed/35884996
http://dx.doi.org/10.3390/biomedicines10071692

Ejemplares similares