The Cytoprotective, Cytotoxic and Nonprotective Functional Forms of Autophagy Induced by Microtubule Poisons in Tumor Cells—Implications for Autophagy Modulation as a Therapeutic Strategy

Microtubule poisons, as is the case with other antitumor drugs, routinely promote autophagy in tumor cells. However, the nature and function of the autophagy, in terms of whether it is cytoprotective, cytotoxic or nonprotective, cannot be predicted; this likely depends on both the type of drug studi...

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Detalles Bibliográficos
Autores principales: Xu, Jingwen, Elshazly, Ahmed M., Gewirtz, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312878/
https://www.ncbi.nlm.nih.gov/pubmed/35884937
http://dx.doi.org/10.3390/biomedicines10071632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312878/
https://www.ncbi.nlm.nih.gov/pubmed/35884937
http://dx.doi.org/10.3390/biomedicines10071632

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