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Analysis of Alternative mRNA Splicing in Vemurafenib-Resistant Melanoma Cells

SIMPLE SUMMARY: Alternative splicing (AS) is one of the hallmarks of human cancer. One of the most common mechanisms of vemurafenib resistance in malignant melanoma is AS of BRAF, occurring in 15–30% of patients. The aim of our study was to investigate the transcriptome and AS D04landscape in the is...

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Detalles Bibliográficos
Autores principales: Bokharaie, Honey, Kolch, Walter, Krstic, Aleksandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312936/
https://www.ncbi.nlm.nih.gov/pubmed/35883549
http://dx.doi.org/10.3390/biom12070993