KHK, PNPLA3 and PPAR as Novel Targets for the Anti-Steatotic Action of Bempedoic Acid

Bempedoic acid (BemA) is an ATP-citrate lyase (ACLY) inhibitor used to treat hypercholesterolemia. We studied the anti-steatotic effect of BemA, and the mechanisms involved, in a model of fatty liver in female rats obtained through the administration of a high-fat diet supplemented with liquid fruct...

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Detalles Bibliográficos
Autores principales: Velázquez, Ana Magdalena, Bentanachs, Roger, Sala-Vila, Aleix, Lázaro, Iolanda, Rodríguez-Morató, Jose, Sánchez, Rosa María, Laguna, Juan Carlos, Roglans, Núria, Alegret, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312949/
https://www.ncbi.nlm.nih.gov/pubmed/35884822
http://dx.doi.org/10.3390/biomedicines10071517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312949/
https://www.ncbi.nlm.nih.gov/pubmed/35884822
http://dx.doi.org/10.3390/biomedicines10071517

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