TIRAP/Mal Positively Regulates TLR8-Mediated Signaling via IRF5 in Human Cells
Toll-like receptor 8 (TLR8) recognizes single-stranded RNA of viral and bacterial origin as well as mediates the secretion of pro-inflammatory cytokines and type I interferons by human monocytes and macrophages. TLR8, as other endosomal TLRs, utilizes the MyD88 adaptor protein for initiation of sign...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312982/ https://www.ncbi.nlm.nih.gov/pubmed/35884781 http://dx.doi.org/10.3390/biomedicines10071476 |