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Tauroursodeoxycholic Acid Reduces Neuroinflammation but Does Not Support Long Term Functional Recovery of Rats with Spinal Cord Injury

The bile acid tauroursodeoxycholic acid (TUDCA) reduces cell death under oxidative stress and inflammation. Implants of bone marrow-derived stromal cells (bmSC) are currently under investigation in clinical trials of spinal cord injury (SCI). Since cell death of injected bmSC limits the efficacy of...

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Detalles Bibliográficos
Autores principales: Wu, Siyu, García-Rama, Concepción, Romero-Ramírez, Lorenzo, de Munter, Johannes P. J. M., Wolters, Erik Ch., Kramer, Boris W., Mey, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313003/
https://www.ncbi.nlm.nih.gov/pubmed/35884805
http://dx.doi.org/10.3390/biomedicines10071501