Cargando…

An Ovarian Steroid Metabolomic Pathway Analysis in Basal and Polycystic Ovary Syndrome (PCOS)-like Gonadotropin Conditions Reveals a Hyperandrogenic Phenotype Measured by Mass Spectrometry

Prior work has demonstrated that murine ovarian explants and isolated ovarian follicles can recapitulate human-like 28-day cycles in vitro with normal patterns of estradiol and progesterone secretion in response to gonadotropin stimulation. The objective of this study was to manipulate the gonadotro...

Descripción completa

Detalles Bibliográficos
Autores principales: Gargus, Emma S., Bae, Yeunook, Chen, Jiexi, Moss, Kristine J., Ingram, Asia N., Zhang, Jiyang, Montgomery, Nathan T., Boots, Christina E., Funk, William E., Woodruff, Teresa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313004/
https://www.ncbi.nlm.nih.gov/pubmed/35884951
http://dx.doi.org/10.3390/biomedicines10071646