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An Ovarian Steroid Metabolomic Pathway Analysis in Basal and Polycystic Ovary Syndrome (PCOS)-like Gonadotropin Conditions Reveals a Hyperandrogenic Phenotype Measured by Mass Spectrometry
Prior work has demonstrated that murine ovarian explants and isolated ovarian follicles can recapitulate human-like 28-day cycles in vitro with normal patterns of estradiol and progesterone secretion in response to gonadotropin stimulation. The objective of this study was to manipulate the gonadotro...
Autores principales: | Gargus, Emma S., Bae, Yeunook, Chen, Jiexi, Moss, Kristine J., Ingram, Asia N., Zhang, Jiyang, Montgomery, Nathan T., Boots, Christina E., Funk, William E., Woodruff, Teresa K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313004/ https://www.ncbi.nlm.nih.gov/pubmed/35884951 http://dx.doi.org/10.3390/biomedicines10071646 |
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