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In Vivo Tracking for Oncolytic Adenovirus Interactions with Liver Cells

Hepatotoxicity remains an as yet unsolved problem for adenovirus (Ad) cancer therapy. The toxic effects originate both from rapid Kupffer cell (KCs) death (early phase) and hepatocyte transduction (late phase). Several host factors and capsid components are known to contribute to hepatotoxicity, how...

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Detalles Bibliográficos
Autores principales: Naumenko, Victor A., Vishnevskiy, Daniil A., Stepanenko, Aleksei A., Sosnovtseva, Anastasiia O., Chernysheva, Anastasiia A., Abakumova, Tatiana O., Valikhov, Marat P., Lipatova, Anastasiia V., Abakumov, Maxim A., Chekhonin, Vladimir P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313019/
https://www.ncbi.nlm.nih.gov/pubmed/35885002
http://dx.doi.org/10.3390/biomedicines10071697