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PD-1/PD-L1 Pathway: A Therapeutic Target in CD30+ Large Cell Lymphomas

The programmed death-ligands, PD-L1 and PD-L2, reside on tumor cells and can bind with programmed death-1 protein (PD-1) on T-cells, resulting in tumor immune escape. PD-1 ligands are highly expressed in some CD30+ large cell lymphomas, including classic Hodgkin lymphoma (CHL), primary mediastinal l...

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Detalles Bibliográficos
Autores principales: Xie, Wei, Medeiros, L. Jeffrey, Li, Shaoying, Tang, Guilin, Fan, Guang, Xu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313053/
https://www.ncbi.nlm.nih.gov/pubmed/35884893
http://dx.doi.org/10.3390/biomedicines10071587